If you thought 2020 was an unpredictable year, you probably weren’t paying attention. For over a decade, epidemiologists have sounded the warning that a once-in-a-hundred-years pandemic could ravage the planet, and that even the most advanced nations were ill-prepared for the fallout. In 2021, we will face challenges both familiar and unforeseen—but we will also see shoots of rejuvenation as the world thaws from lockdown. Here are Fortune’s predictions of how the next year will play out. Read more at Fortune.